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How is it treated?
Treatment
for achalasia includes oral medications, dilation or stretching of the
lower oesophageal sphincter, surgery to cut the sphincter (myotomy), and
injection of muscle-relaxing medicines (botulinum toxin) into the sphincter.
All of these treatments reduce the pressure within the lower oesophageal
sphincter and allow easier passage of food from the oesophagus into the
stomach.
Oral
medications. Drugs such as nitrates and calcium channel blockers can be
used to relax the lower oesophageal sphincter. Only about 10% of patients
benefit from drugs so it is usually reserved for elderly patients who
are not suitable for dilation or surgery or as a temporary measure while
other treatments are considered.
Dilation.
The patient swallows a tube with a balloon on the end. The balloon is
positioned at the lower oesophageal sphincter and then blown up suddenly,
stretching the sphincter. The success rate is 70-80%. Dilation is fast,
inexpensive compared with surgery, and requires only a short hospital
stay. Up to half of patients require more than one dilation.
Dilations
that are unsuccessful may be repeated but the rate of success decreases
with each additional dilation.
The
main complication of forceful dilation is rupture of the oesophagus, which
occurs in 5% of cases. Some of these perforations may heal without surgery
but others will need surgery. Surgery to treat achalasia (myotomy) can
be done at the same time.
Surgery (Heller Myotomy, Oesophagomyotomy). The muscle fibres of the lower
oesophageal sphincter are cut surgically. This can be done using a large
abdominal incision or laparoscopically through small punctures in the
abdomen (keyhole surgery).
Acid
reflux is a side effect after this procedure for 10-15% of patients. In
order to prevent this, the oesophagomyotomy may be modified so that it
doesn’t completely cut the sphincter or it may be combined with
anti-reflux surgery (fundoplication).
Because
of excellent results, (successful in 80-95% of patients), a short hospital
stay (24-48 hours), and fast recovery time, laparoscopic heller myotomy
combined with partial fundoplication is considered the treatment of choice
for achalasia.
Botulinum toxin
This is the newest treatment for achalasia. Botulinum toxin is injected
into the lower sphincter. It is fast, safe, and requires no hospitalisation.
However, the effects on the sphincter often last only for months, and
additional injections with botulinum toxin may be necessary. Injection
is a good option for elderly patients or those who are high risk for surgery.
Are there any complications?
Complications
of achalasia include weight loss and aspiration pneumonia. Oesophagitis
(inflammation of the oesophagus) and oesophageal ulcerations can also
occur. |